OrthoSpin is developing a smart external fixation system designed to allow real-time physician follow-up and reduce dependence on patient compliance. The system is composed of a strut powered by a lightweight motor and a control box placed on top of a circular hexapod fixation frame. The system automatically and continuously adjusts and lengthens the struts according to the prescribed treatment regimen, without patient involvement.

With OrthoSpin's smart system, physicians can be assured that the prescribed course of treatment is being followed. The company's proprietary software program allows physicians to chart patient progress and change the treatment schedule if necessary.

In September 2019, the company received regulatory clearance from the FDA for its smart robotic external fixation system for orthopedic treatment. In January 2021, the company received regulatory clearance from the FDA for its second-generation robotic, digitally enabled external fixation system for orthopedic treatments. The OrthoSpin G2 system is approved in Israel, cleared for use in the United States, and can be used with the DePuy Synthes MAXFRAME Multi-Axial Correction System.

OrthoSpin is part of the Trendlines Group.