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Home > Companies > Raziel Therapeutics
Claimed by owner Last Update 7.12.2021 Suggest Edits Claim Profile
Claimed by owner
Raziel Therapeutics logo

Raziel Therapeutics

Injectable Drug for Treatment of Obesity

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Raziel Therapeutics
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About

Raziel Therapeutics is a clinical-stage pharmaceutical company developing a proprietary drug for targeted fat reduction. The company has developed a new chemical entity that converts white adipose tissue (WAT) into brown adipose tissue (BAT) after a single injection into subcutaneous fat, potentially providing a new way to treat people who are overweight or obese.

Raziels primary drug candidate is RZL-012, an injectable drug that is currently in preclinical development. RZL-012 is administered by several injections delivered in a single injection session. Once injected, RZL-012 triggers immediate fat-cell death, followed by a transient inflammatory process that lasts about a month during which necrotic fat tissue is replaced by fibrotic tissue. This results in a significant long-term, sustained shrinkage of fat tissue.

The companys products are based on work by the team led by Professor Muli Ben-Sasson, who discovered a family of compounds that are able to influence the fate of fat-tissue cells (adipocytes) and convert them from WAT to BAT tissues.

In November 2019, Raziel received FDA approval to develop RZL-012 as an orphan drug for Dercums disease.

Founded

Business models

B2B

Employees

Product stage

Primary Sector

Life Sciences & HealthTech

Products

RZL-012

Geographic markets

Israel, China

Funding

Total Funding

$27.1M

Last Funding

$22M

Funding Stage

C

Total Rounds

3

Investors

9

The Team

(3)
AB
Alon Bloomenfeld
CEO
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EB
Eran Blaugrand
VP R&D
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RG
Racheli Gueta
Clinical Trials Manager
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Company Lifecycle

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Public Offerings & Exits

Private Equity Funding

Seed
$600K
Dec 2014
2 Investors
$600K
A Round
$4.5M
Feb 2016
2 Investors
$4.5M
C Round
$22M
Dec 2019
6 Investors
$22M

Others

Academic Techonology
Aug 2012
undefined Proprietary drug for targeted fat reduction

Locations

Israel

Prof. Menahem Plaut Street 10, Rehovot, Israel

Offices Abroad

Sector

Life Sciences & HealthTech
Pharma & Biomedicine
Discovery & Development

Core Technology

Biologicals

Target Customer

Healthcare & Life Sciences
Healthcare
Patients
Life Sciences
Pharmaceuticals

Tags

(11)

Locations

Israel

Prof. Menahem Plaut Street 10, Rehovot, Israel

Offices Abroad

Notes

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