SynCath Neuroscience is a preclinical-stage medical technology start-up developing ECG-synchronized dynamic ICP-modulation technology. The technology is realized via a disposable, autonomous ICP-modulation probe. The probe is in-dwelling, ECG synchronized, and delivered via an external ventricular drain (EVD)-like catheter.

The underlying physical mechanism is that externally superimposed fine-volume perturbations can be used to enhance cerebral blood flow with synchronized deflateinflate actions within each cardiac cycle. SynCath will initially address patients instrumented with an EVD.