Meir Azulay

BPL Biologics (BioPharm Labs LTD) is a CDMO (Contract Development & Manufature Organization) for the biotech sector since 2005. (>200 projects; >100 Customers- startups & established companies) Our capabilities include: Clone development (mammalian, bacterial, yeast) Process Development: Fermentation, purification, API formulation, analytical methods Production: gram scale batches to supply pre-clinical studiesBio-XL is a privately owned entreprenurial company, focusing on protein based drug development. Portfolio companies: Klothix Biopharmaceuticals and Akivir Biomedical Klothix develops anti-cancer drug treatment based on KLOTHO hormone. Klotho has unique and specific MoA as it affects cancer cells in their differences from normal cells. Recombinant Klotho 9rhKL) showed in various in-vitro and animal studies efficacy in reducing tumor size and inhibition cancer cell growth of different malignancies. The drug has a unique Mechanism of Action, never tested in humans, demostrating efficacy and good safety profile. Akivir develops drug treament for kidney diseases. The MoA is anti-apoptotic. The drug is developed for the following indications: -Improved preservation of transplanted kidney -Prevention of AKI in medical procedures where kidney safety compromised (cardia surgeries demanding ischemia; use of nephrotoxic agents: chemotherpay, contrast media, biological drugs, antibiotics)