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    News Analysis

    Companies developing technologies related to Mental Health

    The companies in this list are those committed to develop technologies for mental health. They make use of cutting-edge advancements including AI-driven therapeutic platforms, mood-monitoring wearable tech, and telemedicine services for mental wellbeing

    Myndlift

    Accessible Home Neurofeedback Platform
    Myndlift provides tools for enhancing cognitive abilities without medication or side effects by relying on an accessible, affordable, evidence-based technique. The company offers a therapist-guided neurofeedback solution where patients can do the training from home while being monitored by certified therapists, thus lowering the costs of making this solution accessible to the wider public. Myndlift's technology is based on neurofeedback, an intervention that measures brain activity and retrains the brain.

    Locations

    Israel

    Derech Menachem Begin 150, Tel Aviv-Yafo, Israel

    Offices Abroad

    650 California Street, San Francisco, CA, United States

    Total funding

    $3.2M

    Funding stage

    Seed

    Number of employees

    11-50

    Founded

    6/2014
    Israel Offices
    Derech Menachem Begin 150, Tel Aviv-Yafo, Israel
    Offices Abroad
    650 California Street, San Francisco, CA, United States

    Genetika+

    Personalized Treatment Solutions for Depression
    Genetika+ is developing a personalized medical testing tool to better treat depression by helping physicians find the best drug therapy for their patients. The Genetika+ test predicts the best drug treatment for each patient, enabling faster treatment, fewer side effects, and lower dosing.

    Locations

    Israel

    Professor Racah St 3, Jerusalem, Israel

    Total funding

    $30.5M

    Funding stage

    A

    Number of employees

    11-50

    Founded

    1/2018
    Israel Offices
    Professor Racah St 3, Jerusalem, Israel

    Reflect Innovation

    Biofeedback-based Stress Management
    Reflect Innovation has created a product for managing stress. It is a portable, interactive, smart, and soft textile ball that utilizes biofeedback to help practice relaxation and reduce anxiety using a calming emanating light.

    Locations

    Israel

    HaMenofim St 11, Herzliya, Israel

    Total funding

    $3.78M

    Funding stage

    Seed

    Number of employees

    11-50

    Founded

    6/2018
    Israel Offices
    HaMenofim St 11, Herzliya, Israel

    Brain1

    Brainwave Entrainment Device
    Brain1 is the developer of BrainWavez, a consumer device that uses brainwave entrainment technology to help users improve their quality of life in a variety of areas. Based on over 20,000 publications and research studies, including from the Technion and NASA, the company’s technology aims to increase focus and boost energy, improve learning, deploy Schumann resonances, reduce stress, facilitate meditation, help users fall asleep faster, and improve symptoms of Alzheimer’s disease using 40 Hz light therapy.

    Locations

    Israel

    HaMenofim Street 11, Herzliya, Israel

    Total funding

    $800K

    Funding stage

    Mature

    Number of employees

    1-10

    Founded

    12/2015
    Israel Offices
    HaMenofim Street 11, Herzliya, Israel

    Lin Health

    Personalized Online Care for Chronic Pain Management
    Lin is an online chronic pain care plan that delivers integrative, personalized, science-based solutions by pain experts who really care. Users are paired with a personal health coach (a real person) who considers their full pain history and takes the time to get to know each member and how pain impacts their lives. Lin members then meet one-on-one with a medical professional who builds a personalized care plan around the user's needs and specific health goals. The care team will collaborate on the user's case and helps them work through their plan. Subscribers have unlimited access to their health coach, who will monitor their progress, make adjustments to their care plan as needed, and stick with them as long as the user needs support with their pain relief.

    Locations

    Israel

    Tel Aviv, Israel

    Offices Abroad

    Denver, CO, USA

    Total funding

    $15.2M

    Funding stage

    A

    Number of employees

    51-200

    Founded

    1/2021
    Israel Offices
    Tel Aviv, Israel
    Offices Abroad
    Denver, CO, USA

    Taliaz

    Predictive Technology for Personalized Medication
    Taliaz is the developer of Predictix, an AI-based branded platform designed to help doctors deliver personalized medicine. Based on proprietary IP, Predictix generates doctor-centric therapy prediction reports for individual patients. The Predictix reports are managed as a decision-support tool, enabling general practitioners and specialists to make informed treatment choices for improved patient outcomes. The companys flagship application addresses depression. The Predictix Anti-Depressant AI system is a noninvasive, user-friendly application that analyzes genomic, clinical, and demographic data to generate a personalized report that includes statistical analysis on the efficacy of antidepressants and their side effects, allowing doctors to optimize antidepressant treatment strategies for enhanced patient outcomes. The application is currently available for commercial use in the EU and Israel. Taliaz mission is to empower doctors and patients with artificial intelligence technology to improve the assessment, treatment, and management of mental health disorders.

    Locations

    Israel

    Kaufmann St 2, Tel Aviv-Yafo, Israel
    Kaufmann St 2, Tel Aviv-Yafo, Israel

    Total funding

    $3.2M

    Funding stage

    Mature

    Number of employees

    11-50

    Founded

    8/2012
    Israel Offices
    Kaufmann St 2, Tel Aviv-Yafo, Israel
    Kaufmann St 2, Tel Aviv-Yafo, Israel

    Laguna Health

    AI-powered Contextual Care Management Solution
    Laguna Health is an AI-powered contextual care management solution, scaling personalized care outside the four walls of the hospital. The company has built a natural language processing and AI care personalization engine proven in randomized clinical trials to drive 50% cost savings and 10X efficiency gains for care managers. Laguna focuses on hospital to home care journeys, driving over 40% of payor spend. Laguna's customers include health plans and integrated delivery networks, using the Laguna platform to drive care management productivity.

    Locations

    Israel

    Tel Aviv, Israel

    Offices Abroad

    100 Park Ave, New York, NY 10017, USA

    Total funding

    $21.6M

    Funding stage

    A

    Number of employees

    11-50

    Founded

    4/2020
    Israel Offices
    Tel Aviv, Israel
    Offices Abroad
    100 Park Ave, New York, NY 10017, USA

    GrayMatters Health

    Digital Therapy for Mental Health
    GrayMatters Health (GMH) develops digital self-neuromodulation therapeutics for mental disorders to help patients regain agency over their emotion regulation. GMH offers Prism, a noninvasive adjunct therapeutic that utilizes novel neuroscience-based and brain-mechanism-specific biomarkers. The company's first product candidate, Prism for post-traumatic stress disorder (PTSD), is undergoing clinical investigation in five sites across the United States and Israel, to demonstrate its efficacy and safety as an adjunct to standard PTSD treatments. Our first product, Prism for PTSD, was cleared by FDA in March 2023. The novel technology was developed by Professor Talma Hendler and her team at Tel Aviv Sourasky Medical Center and Tel Aviv University.

    Locations

    Israel

    Derech HaAtsma'ut 82, Haifa, Israel

    Total funding

    $18.3M

    Funding stage

    A

    Number of employees

    11-50

    Founded

    10/2018
    Israel Offices
    Derech HaAtsma'ut 82, Haifa, Israel

    Firefly Neuroscience

    Measuring Brain Health
    Firefly Neuroscience aims to improve outcomes associated with mental illnesses by providing clinicians and patients with an objective and comparable age-matched assessment of how their brain is functioning (cognition). Its FDA-cleared Brain Network Analytics technology is used by healthcare practitioners to support treatment options and assess whether a treatment is working. Firefly harnesses the power of brain mapping, signal processing, big data, and artificial intelligence to improve mental health and patient outcomes, globally. Firefly Neuroscience leverages technical advances in computing to deconstruct and analyze how the brain is functioning, making them clinically useful for front-line clinicians to objectively measure, monitor, and manage brain function.

    Locations

    Israel

    Arieh Shenkar St 1, Hertsliya, Israel

    Offices Abroad

    407 Iroquois Shore Rd, Oakville, ON L6H 1M3, Canada
    1100 Military Rd, Buffalo, NY 14217, USA

    Total funding

    $61.39M

    Funding stage

    E

    Number of employees

    11-50

    Founded

    1/2006
    Israel Offices
    Arieh Shenkar St 1, Hertsliya, Israel
    Offices Abroad
    407 Iroquois Shore Rd, Oakville, ON L6H 1M3, Canada
    1100 Military Rd, Buffalo, NY 14217, USA

    VoiceSense

    Predictive Speech Analytics
    Voicesense specializes in behavioral, predictive speech analytics. The company's award-winning technology analyzes hundreds of speech parameters, leveraging the non-content, acoustic components of speech, such as intonation, pace, and emphasis, and links these patterns to behavioral and personal characteristics. Voicesense analyzes this language-independent and culturally unbiased data using machine-learning techniques and provides personalized predictions of a person's behavior applicable to a wide range of fields including risk management, human capital recruiting and retention, sales conversion, and healthcare.

    Locations

    Israel

    Shim'on Ha'tsadik St 12, Tel Aviv-Yafo, Israel

    Offices Abroad

    26 S Rio Grande St #2072, Salt Lake City, UT 84101, USA

    Total funding

    $11M

    Funding stage

    A

    Number of employees

    11-50

    Founded

    7/2016
    Israel Offices
    Shim'on Ha'tsadik St 12, Tel Aviv-Yafo, Israel
    Offices Abroad
    26 S Rio Grande St #2072, Salt Lake City, UT 84101, USA

    Eleos Health

    Automated Behavioral Care Workflow Solution
    Eleos Health specializes in CareOps automation, offering a solution designed to free clinicians from time-consuming operational burdens by consolidating the entire behavioral care workflow, from progress notes to session intelligence. The company is focused on automating operational necessities, including all documentation and compliance administration, as well as providing deep clinical insights through session intelligence. Eleos aims to make evidence-based behavioral care a reality so that clinicians, providers, and networks can track treatment and progress in a measurable and comparative way.

    Locations

    Israel

    Menachem Begin Road 136, Tel Aviv-Yafo, Israel

    Offices Abroad

    Boston, MA, USA

    Total funding

    $68M

    Funding stage

    B

    Number of employees

    51-200

    Founded

    4/2019
    Israel Offices
    Menachem Begin Road 136, Tel Aviv-Yafo, Israel
    Offices Abroad
    Boston, MA, USA

    Sequel.Care

    Mental Healthcare
    SequelCare is a measurement-based platform that lets mental healthcare providers actively engage patients and their inner circle and provides data, analytics, and actionable insights to hone treatment planning and decision-making. SequelCare’s mental healthcare platform offers data-driven, measurement-based care for mental illnesses. The company's holistic, collaborative platform empowers mental healthcare providers to develop, execute, and manage treatment plans, actively engage circle-of-care members, and ensure that each party has the information they need. In so doing, the company aims to facilitate streamlined, effective care paths that lead to the best possible mental healthcare outcomes.

    Locations

    Israel

    Haifa, Israel

    Offices Abroad

    730 Arizona Ave, Santa Monica, CA, USA

    Total funding

    $1.75M

    Funding stage

    Pre-Seed

    Number of employees

    11-50

    Founded

    1/2018
    Israel Offices
    Haifa, Israel
    Offices Abroad
    730 Arizona Ave, Santa Monica, CA, USA

    Mindtension

    Rapid Diagnostic Platform for Measuring ADHD
    MindTension offers an affordable, ultra-precise, rapid diagnostic platform that measures signs of ADHD in just six minutes. MindTension uses an electromyography (EMG) system to measure reflexive responses to auditory stimuli and levels of inhibition; the more exaggerated the response, or the lower the level of inhibition, the more serious the condition. The company’s accurate, in-office diagnostic procedure enables therapists to immediately measure the effects of ADHD medication and make adjustments in order to identify the smallest dose required to produce the desired outcome. MindTension was developed based on 10 years of research at the Technion.

    Locations

    Israel

    Sha'ar HaNegev Regional Council, Israel

    Total funding

    $5M

    Funding stage

    Seed

    Number of employees

    1-10

    Founded

    7/2020
    Israel Offices
    Sha'ar HaNegev Regional Council, Israel

    Healables

    Wearable Electrotherapy Devices
    Healables is an AI Health Technology company on a mission to transform human health, performance, recovery and rehabilitation with personalized, bioelectric wearables for in-clinic, hybrid and remote care. Healables is the inventor of patented Electron Stream Microcurrent Technology including its smart e-textiles, which is currently being commercialized in four verticals: Sports, Automotive, Military and Medical, through its first product line, ElectroGear Sports, ElectroGear Automotive, ElectroGear Military and Medical, with an emphasis on non-steroidal, non-NSAID and non-opioid solutions for musculoskeletal issues, inflammation conditions and pain relief, optimized for patients to use on their own at home, in a clinic, or in a hybrid home/clinic continuum of care.

    Locations

    Israel

    Ha-Tsvi Street 15, Jerusalem, Israel
    Hadassah University Hospital - Ein Kerem - BIOHOUSE

    Total funding

    $2.28M

    Funding stage

    Seed

    Number of employees

    11-50

    Founded

    12/2017
    Israel Offices
    Ha-Tsvi Street 15, Jerusalem, Israel
    Hadassah University Hospital - Ein Kerem - BIOHOUSE

    VIVID

    Creator economy platform for personal growth experts
    VIVID has developed an online solution for turning wellbeing into effective practice, combining tailor-made concrete practice plans made by personal growth experts.

    Locations

    Israel

    Tel Aviv-Yafo, Israel

    Total funding

    $800K

    Funding stage

    Pre-Seed

    Number of employees

    1-10

    Founded

    8/2022
    Israel Offices
    Tel Aviv-Yafo, Israel

    Circles

    Online Support Group Platform
    Circles is an emotional support platform that ensures no one has to overcome life's challenges alone. Circles enables people to be heard, understood, and supported by others who are going through the same issues in their lives, such as the loss of a loved one, parenting issues, or divorce. By connecting users in safe, intimate, and private groups led by professional facilitators, Circles aims to help people heal. Circles groups meet live for 60-minute video meetings and also have the ability to message via online chat at any time. Circles users can also access personalized content, including self-help exercises, blogs, and webinars, at no extra cost.

    Locations

    Israel

    HaArba'a Street, Tel Aviv-Yafo, Israel

    Offices Abroad

    140 2nd Street, San Francisco, CA, USA

    Total funding

    $24.5M

    Funding stage

    A

    Number of employees

    51-200

    Founded

    1/2020
    Israel Offices
    HaArba'a Street, Tel Aviv-Yafo, Israel
    Offices Abroad
    140 2nd Street, San Francisco, CA, USA

    myAir

    Data-driven Personalized Plant-based Nutrition for Stress Management
    MyAir is a data-driven smart wellness company offering a solution to deal with chronic stress. MyAir leverages artificial intelligence to personalize stress relief via nutrition and mind–body analytics. Based on physiological and psychological parameters, myAir combines functional, personalized nutrition recommendations with tailored insights to increase stress resilience with a dynamic feedback loop. GARMIN and myAir published research results proving an 80% decrease in stress. Amazon AWS, Moovit (Intel), banks, and thousands of US customers have already used myAir's stress resilience platform with high satisfaction and engagement rates.

    Locations

    Israel

    Tel Aviv, Israel

    Offices Abroad

    New Jersey, USA
    California, USA

    Total funding

    $8M

    Funding stage

    Seed

    Number of employees

    11-50

    Founded

    6/2019
    Israel Offices
    Tel Aviv, Israel
    Offices Abroad
    New Jersey, USA
    California, USA

    miCure Therapeutics

    MicroRNA Therapeutics for CNS Disorders
    miCure Therapeutics is a biotechnology company leveraging microRNA-based therapeutics and diagnostics for neurodegenerative and psychiatric disorders. Its microRNA therapeutics and diagnostics for central nervous system (CNS) disorders are based on inventions by Professor Alon Chen of the Department of Neurobiology and Dr. Eran Hornstein of the Department of Molecular Genetics at the Weizmann Institute of Science. miCure Therapeutics miR-135 is being developed to treat mood disorders, in particular major depression and treatment-resistant depression, a major unmet medical need with few therapeutic options currently available for patients and physicians. miR-135 targets, among others, two important gene transcripts, Htr1a (serotonin receptor-1a) and Slc6a4 (serotonin transporter), both essential for intact serotonergic neuronal activity.

    Locations

    Israel

    Weizmann St 2, Tel Aviv-Yafo, Israel

    Total funding

    $2M

    Funding stage

    Mature

    Number of employees

    1-10

    Founded

    9/2013
    Israel Offices
    Weizmann St 2, Tel Aviv-Yafo, Israel

    Empathy

    Digital Companion for Navigating Bereavement
    Empathy's app helps families through the financial, legal, emotional, and logistical challenges of losing a loved one. The Empathy app includes personalized task navigation, one place to securely save important documents, and real-time chat with loss experts. The app also automates processes related to estate management.

    Locations

    Israel

    Ha-Arba'a Street 28, Tel Aviv-Yafo, Israel

    Offices Abroad

    27 E 28th St, New York, NY, USA

    Total funding

    $43M

    Funding stage

    A

    Number of employees

    51-200

    Founded

    7/2020
    Israel Offices
    Ha-Arba'a Street 28, Tel Aviv-Yafo, Israel
    Offices Abroad
    27 E 28th St, New York, NY, USA

    Pery

    Support System for Improving Clinical Outcomes of Children's ADHD Treatment
    Pery is pioneering a new era in ADHD parenting support within the caregiver AI category. As a comprehensive solution, Pery transcends traditional roles—going beyond diagnosis or treatment to become the singular destination for ADHD families. Harnessing cutting-edge technology, including Large Language Models (LLMs) and a clinically validated knowledge base, Pery serves as a tech-driven ally, offering real-time strategies and automated tools to revolutionize the ADHD parenting experience.

    Locations

    Israel

    Tel Aviv, Israel
    Dallas, TX, USA

    Primary sector

    Total funding

    $5.7M

    Funding stage

    Seed

    Number of employees

    11-50

    Founded

    8/2021
    Israel Offices
    Tel Aviv, Israel
    Dallas, TX, USA

    XRHealth

    Virtual Clinic for Rehabilitation and Therapeutic Care
    XRHealth is focused on bringing patient care into the virtual world. The company operates therapeutic care virtual rooms through the use of proprietary FDA- and CE-registered medical extended reality (XR) technology, including virtual and augmented reality. XRHealth integrates immersive XR technology, licensed clinicians, and advanced data analytics on one platform, providing a comprehensive therapeutic care solution that enables patients to receive treatment from the comfort of home. The company offers a variety of patent-pending solutions ranging from rehabilitation services to cognitive assessment and training to pain management. XRHealth works with several world-renowned U.S. healthcare providers, hospitals, and rehabilitation centers.

    Locations

    Israel

    Shoken 32, Tel Aviv-Yafo, Israel

    Offices Abroad

    200 Highland Ave, Needham, MA 02494, USA

    Total funding

    $38.08M

    Funding stage

    A

    Number of employees

    51-200

    Founded

    7/2016
    Israel Offices
    Shoken 32, Tel Aviv-Yafo, Israel
    Offices Abroad
    200 Highland Ave, Needham, MA 02494, USA

    One World Cannabis

    Cannabis Treatment Products
    One World Cannabis discovers, develops, and commercializes cannabis-based therapeutic products and treatments. One World Cannabis intends to investigate specific cannabis strains, combinations of the cannabinoids THC and CBD, and optimal dosages. The companys first clinical trials will explore potential treatments for fibromyalgia, psoriasis, basal cell carcinoma, post-traumatic stress disorder, and seizures. The second set of clinical trials will focus on the development of cannabis medicines for Crohns disease, Parkinsons disease, Tourettes syndrome, migraines, chronic pain, Alzheimers disease, pediatric epilepsy, prostate cancer, and diabetes. One World Cannabis is a wholly owned Israeli subsidiary of OWC Pharmaceutical Research Corp.

    Locations

    Israel

    Ben Gurion Road 2, Ramat Gan, Israel

    Total funding

    $2M

    Funding stage

    Public

    Number of employees

    1-10

    Founded

    1/2008
    Israel Offices
    Ben Gurion Road 2, Ramat Gan, Israel

    Neurolief

    Brain Neuromodulation Technology
    Neurolief develops treatments for patients with chronic neurological and neuropsychiatric disorders. The company has created a digital therapeutics platform of clinically proven neuromodulation-based solutions that can be delivered to patients at home or in the community. Neuroliefs Relivion is a noninvasive multichannel brain neuromodulation system for treating neurological and neuropsychiatric disorders. It offers precise, personalized care by delivering stimulation to six branches of the occipital and trigeminal nerves via three adaptive output channels. This creates a cumulative effect by releasing neurotransmitters in the brainstem to modulate the brain networks associated with pain and mood control. The Relivion device is placed comfortably on the patients head, where it stimulates the nerves. The connected e-Relief mobile app displays the treatment status and transmits information between the patient and the cloud. The Relivion system is FDA approved and CE marked and has been granted breakthrough device designation by the FDA.

    Locations

    Israel

    Sderot Giborei Israel 12, Netanya, Israel

    Offices Abroad

    Tampa, FL, USA

    Total funding

    $5.3M

    Funding stage

    Mature

    Number of employees

    11-50

    Founded

    8/2013
    Israel Offices
    Sderot Giborei Israel 12, Netanya, Israel
    Offices Abroad
    Tampa, FL, USA

    Sensi.Ai

    In-home Virtual Care Platform
    Sensi.ai is an in-home virtual care agent for home health agencies and senior care providers. The Sensi platform leverages artificial intelligence to enable care agencies to offer round-the-clock services, despite the massive shortage of caregivers and regardless of the patients financial capacity to afford 24/7 care. The Sensi platform delivers audio analytics-based insights designed to help eliminate blind spots and to provide agencies with complete visibility and transparency into each hour of care without having to rely on input from either the caregiver or the client. Off-shift, Sensi serves as a much-needed safety net, providing seniors with both confidence and independence in a safe, monitored environment, all without compromising their privacy.

    Locations

    Israel

    Derech Menachem Begin 90, Tel Aviv-Yafo, Israel

    Offices Abroad

    Danville, CA, USA

    Total funding

    $17.65M

    Funding stage

    A

    Number of employees

    51-200

    Founded

    1/2019
    Israel Offices
    Derech Menachem Begin 90, Tel Aviv-Yafo, Israel
    Offices Abroad
    Danville, CA, USA

    DarioHealth

    Digital Therapeutics for Treating Chronic Conditions
    DarioHealth is a global digital therapeutics company aiming to revolutionize how people with chronic conditions manage their health, with offerings that include highly rated diabetes and hypertension solutions. The companys AI-powered digital therapeutic solutions are designed to do more than simply support an individuals disease. Dario provides adaptive, personalized experiences that drive behavior change through evidence-based interventions, high-quality software, coaching, and intuitive, clinically proven digital tools to help individuals improve their health and sustain meaningful outcomes. DarioHealth operates at the intersection of life sciences, behavioral science, and software technology and is rapidly expanding into new chronic conditions and geographic markets using a performance-based approach to improve its users health.

    Locations

    Israel

    Ha-Tokhen Street 8, Caesarea, Israel

    Offices Abroad

    London, UK
    142 West 57th Street, New York, NY, USA

    Total funding

    $180.1M

    Funding stage

    Public

    Number of employees

    201-500

    Founded

    9/2011
    Israel Offices
    Ha-Tokhen Street 8, Caesarea, Israel
    Offices Abroad
    London, UK
    142 West 57th Street, New York, NY, USA

    Valera Health

    Comprehensive Behavioral Health Solution
    Valera Health offers personalized mental health services combining meditation, therapy, and medications wrapped around with technology. The company helps organizations expand access to behavioral healthcare. It provides a comprehensive behavioral health solution for employers that gives employees fast access to high-quality mental healthcare. The Valera Health app keeps patients connected to their care team. Using the app, patients can reach out to their health coach or therapist through a secure chat, access a digital library of wellness and meditation programs, and chat face to face with clinicians through an in-app video call. The company also partners with some insurance carriers (such as CDPHP) to offer services directly to their members. Valera Health therapists are highly trained, licensed mental health professionals with expertise in a variety of evidence-based therapy models, including cognitive behavioral therapy, psychoanalysis, mindfulness, and trauma-informed care.

    Locations

    Israel

    Ya'akov Schreiboim St 26, Jerusalem, Israel

    Offices Abroad

    134 North 4th Street, Brooklyn, NY, USA

    Total funding

    $70.7M

    Funding stage

    A

    Number of employees

    201-500

    Founded

    3/2015
    Israel Offices
    Ya'akov Schreiboim St 26, Jerusalem, Israel
    Offices Abroad
    134 North 4th Street, Brooklyn, NY, USA