Promising Companies Recently Selected by the IIA

AccuLine was founded with the vision to save the lives of millions of people worldwide by preventing the next heart attack. AccuLine is developing CORA – an accurate, non-invasive, swift, and cost-effective examination for early detection of CAD, designed to replace the inaccurate, time-consuming, and labor-intensive stress test examinations.

Through a brief 4-minute evaluation of three vital signs - the heart's electrical activity, oxygen saturation levels, and respiratory phase, CORA automatically generates results, ensuring a seamless and efficient process. CORA has the potential to save the lives of millions of patients worldwide, while simultaneously decreasing health care-related costs.

AccuLine has received grants from Google and the Israeli Innovation Authority, and among its shareholders are Mayo Clinic, eHealth Ventures and Maccabi Healthcare Services.

Embie is pioneering in the field of remote fertility management. Our suite of products expands fertility clinics' geographic reach and enhances their operational efficiency. Peer-reviewed research has been published on how our mobile app boosts pregnancy success rates. Our first US clinic customers are signed and set to go live in Q4 of 2024

Picodya introduces game-changing technology with the proven potential to empower diagnostics access worldwide.

Picodya's B-Matrix, microfluidic lab-on-a-chip platform redefines diagnostics, supports simultaneous hybrid testing for both molecular and immunoassays with multiplexed syndromic panels for various sample types. Its innovative multi-use consumables utilization allows for massive cost reduction while the minimal sample volume offers less invasive patients’ experience.
The system unique and modular design supports diverse clinical settings anywhere from a large hospital systems’ laboratory through urgent care settings and physician offices as well as emerging settings such as airports, pharmacies and patients’ homes.

Reborn is developing a portable and safe brain scanner based on ultrasound technology. Reborn's high-resolution 3D imaging system, comparable to a CT scan, can be used anytime, anywhere. With a primary focus on the ICU market, Reborn aims to address challenges associated with extended waiting times, transportation risks, and potential radiation effects.

The implementation of Reborn's scanner is anticipated to yield significant reductions in hospitalization days, infections, and treatment delays, thereby resulting in annual cost savings amounting to billions of dollars for US hospitals.

EndoCure specializes in diagnosing and managing endometriosis, which affects a significant number of women in their reproductive years. Their AI-powered ultrasound system, combined with targeted contrast agents, detects, maps, and stages endometriosis lesions. The technology includes a robotic scanning system that produces 3D images, analyzed by AI to identify lesions, enhancing diagnosis, management, and surgical planning.

Maverick Medical AI is a commercial-stage company that offers a multi-specialty platform that understands unstructured patient reports and autonomously codes them for reimbursement claims. The company's platform, mCoder, uses advanced artificial intelligence and deep-learning technology to generate synthetic data.

Maverick's mCoder deep-learning artificial intelligence understands and converts patient charts into medical codes without coder involvement. The mCoder platform can continuously read large encounter documents and derive all relevant codes with an impressive degree of accuracy.

Maverick's experience indicates that autonomous coding can deliver significant productivity gains three times higher than current coding methods.
Maverick Medical AI has locations in Israel and the United States.

Milagro is leading the change in automating medical coding processes. Its cutting-edge technology eliminates the challenges associated with down coding, denials and the growing shortage of medical coders. By leveraging the power of technology, Milagro enables organizations to meet increasing coding demands while maintaining high levels of accuracy

RespirAI Medical is developing a wearable disease-management platform for home monitoring. The companys technology enables patients to manage multiple health conditions, improving their quality of life and reducing costs to the healthcare system. The system enables changes in patient health to be detected at an early stage, before the patient reports symptoms or experiences physiological decline.

RespirAIs easy-to-wear passive sensing technology captures medical-grade physiological data a few minutes a day for long-term patient monitoring. Deviations from the patients clinical baselines are automatically synced to the cloud for analysis using advanced algorithms and artificial intelligence capabilities, and the results are shared with the patients care team and family.

The systems core technology is based on an invention of researchers from the University of Nebraska at Omaha.

FeelBetter's AI-powered solution identifies patients who are at high risk of near-term hospitalization related to polypharmacy issues, recommends changes to medication regimens and other needed clinical interventions, and comprehensively monitors progress at the individual and population health levels.

FIZE Medical provides the first platform technology to remotely monitor and manage patients with an indwelling Foley catheter. The company developed and manufactures FIZE kUO device which enables digital real-time measurement of kidney urine output and key indicators of the health status of patients found in their urine with customizes alerts, allowing evidence based clinical decision-making .

The Company’s device has been FDA registered and have been tested in clinical trials for efficacy and safety.

NanoGhost is a drug-delivery technology that uses adult stem cells to transport medicine directly to the tumor site. The technology has already proven successful in treating pancreatic, lung, breast, prostate, and brain cancer in mice.

The platform is based on nano-vesicles, termed Nano-Ghosts (NGs), which are technologically reconstructed from the cell membranes of naturally targeted allogeneic mesenchymal stem cells (MSCs), after removing their cytoplasm and nuclei. The NGs' safety and targeting capabilities rely on their retention of the surface-associated mechanisms that govern MSCs' well-documented allogeneic tolerability and targeting of multiple inflamed and malignant tissues.

The NanoGhost technology was developed by Professor Marcel Machluf, the faculty dean of Biotechnology & Food Engineering at the Technion-Israel Institute of Technology. Professor Machluf developed the technology in her lab at the Technion and set up a start-up as a spin-off from the university to commercialize the technology.

Israel's Ministry of Science and Technology named NanoGhost as one of Israel's 60 most impactful developments. The NanoGhost technology has been patented in the United States and Europe, with additional patents pending in India and China.

MNDL Bio's solution focuses on optimizing gene expression in cells to significantly increase protein production yield. Leveraging cutting-edge technology, including advanced algorithms and patented methods, the core technology utilizes Artificial Intelligence (AI) and Machine Learning (ML) based on genomic Big Data.

MNDL enhances the efficiency of biological systems, making them more productive and cost-effective. This has far-reaching applications across various sectors.

The company won the "Coller Startup Competition" for Edition 2023.

BioTip's Freshness Sensor provides the true freshness status of products. The Freshness Sensor monitors microbial growth and changes color when the amount of microbial content is higher than expected.
The Freshness Sensor contains only compounds that are allowed in direct contact with food.
A patent has already been granted in the US, China, and Israel, with an additional patent submitted.

Sufresca develops edible produce coatings to prolong shelf life, reduce food loss and waste, and help create a plastic-free world. The company's solution facilitates longer storage periods, efficient chilling practices, and optimized storage and handling methods while expanding market opportunities and ultimately benefitting consumers.

Sufresca's eco-friendly products enable lower energy consumption by making packaging redundant and optimize the flavor and appearance of fruits and vegetables, including peppers, cucumbers, tomatoes, avocados, mangoes, and citrus. The company's products are FDA and EU regulated.

Kinoko has developed a biological, natural fermentation approach to grow fungi on legumes and grains. With this approach, the company can grow products with high nutritional value, a rich taste, and a 3D structure with juicy texture and wonderful bite.

TuttiPuffs develops a technology that produces the healthy crisps that preserves the vegetable's flavor and nutrition. With two registered patents, the process does not use oil or starches, and it contains over 20% protein, more than 14% fiber, and it's gluten free.

Edete provides precision pollination services for growers using a combination of stored, high-quality pollen and a proprietary mechanical pollination system. Its pollen bank contains all-natural, viable pollen that remains effective for several years and is tailored to specific crop varieties, helping to overcome bloom desynchronization caused by changing climate conditions. Edete’s 2Be mechanical pollinator ensures accurate and timely pollen dispersal, optimizing fertilization and improving yield. The technology can supplement or replace traditional pollination methods, including bees and wind, offering a controlled and scalable alternative for a wide range of crops.

Yofix Probiotics develops and manufactures white-label vegan and soy-free fermented plant-based prebiotic and probiotic foods, based on a blend of cereals, nuts, and seeds. The first released products are plant-based yogurt alternatives and yogurt-alternative drinks, to be followed by desserts, frozen yogurts, and an ice cream base.

Nuversys is a B2B company that developed a patented technology platform to enrich food with essential nutrients. This solution made Nuversys the first and only company in the global ingredients market to successfully solve the challenge of enriching food with several nutrients, including Omega-3.

The company’s product - N-PEARLS - enables food producers to integrate a daily dosage of nutrients into their products. Nuversys has a growing portfolio of N-PEARLS products consisting of vitamins, minerals, oils, and botanicals.

Nuversys aims to impact global health and help people of all ages by offering nutrient-rich ingredients that can be incorporated into delicious and accessible food products, thus providing nutritional food to all populations and providing an alternative for daily supplement intake.

The company is focused on collaborating with food producers to deliver healthy ingredients through foods that consumers love. N-PEARLS were successfully incorporated into different varieties of food products, including dairy, energy bars, ice cream, and alternative protein products.

Nuversys is led by an exceptional multidisciplinary team of experts in the materials science, applied chemistry, engineering, food technology, and nutrition fields.

Omaiko has developed microalgae farming platforms, delivering sustainable and economically viable microalgae production. This groundbreaking system has led to the creation of Omaiko's Protein, a versatile protein ingredient that meets consumer demands and addresses the requirements of food manufacturers.

Biotic has developed a scalable and circular solution for plastics by creating a fully biodegradable and bio-based alternative material made from PHBV (PHA) polymer. This process is environmentally friendly and can seamlessly replace traditional plastic. The PHBV polymer is derived from sea algae, which is a widely available and naturally occurring resource.

ToBe specializes in advanced agri-tech solutions designed to protect honeybee health, addressing critical threats to pollination and global food security. Its flagship product, HiveMaster™, is a next-generation hive management and Varroa mite control system that enhances colony survival and productivity. HiveMaster™ utilizes optimized electro-chemical fumigation technology to eliminate over 98% of Varroa mites while using 90% less active compound than conventional treatments, resulting in stronger colonies and improved pollination efficiency. Additionally, HiveMaster™ serves as a comprehensive hive intelligence platform, offering real-time monitoring, data-driven insights, and enhanced durability and adaptability to help beekeepers optimize colony management.

Evinature was founded on the nexus of two medical philosophies. By bridging the gap between modern and traditional medicine, we’re able to provide more patients with safe and natural remedies that are embraced by the medical community.

We believe it’s time for healthcare to prioritize patient global accessibility to accurate medical assessments and affordable treatments. No patents, no trends, no misinformation. We simply develop, test, prove, then give back to the community.

Tailored Protocols:
No two bodies are the same, which is why we provide evidence-based protocols that address each patient’s condition and state of severity so we can precisely target your individual needs and improve long-term results.

Guided Care:
Regular online follow-ups enable precise adjustments to your protocol so we can address your changing needs throughout treatment. And to ease the way, we also provide complementary clinic support to guide you through the entire process.

Labs:
We’re constantly refining our products through ongoing research and collaborations with over 20 leading medical centers in the U.S, enabling the further development of effective neutraceuticals that are accessible to patients worldwide.

Evidence:
Evinature prioritizes evidence above the trends. We are caregivers by profession, and therefore emphasize product quality and scientific integrity above all else, exclusively distributing products that have passed the golden standard of clinical trials.

By the Patient for the Patient:
Patients are the greatest untapped resource in healthcare, which is why we’ve developed a research database founded on their invaluable experience. At Evinature, each patient contributes to the community simply by taking the assessment. This allows us to constantly expand our research and keep the community updated with vital news and information.