Mitoconix Bio is developing a strategy for improving mitochondrial health as a disease-modifying therapeutic for neurodegenerative diseases.
The companys lead drug is an inhibitor of pathological mitochondrial fragmentation and dysfunction. The drug has demonstrated in vivo efficacy in animal models of Huntingtons disease and Parkinsons disease, and it has shown beneficial activity in patient-derived cells of Huntingtons disease, sporadic and genetic Parkinsons disease, and sporadic and genetic Alzheimers disease.