VYNE Therapeutics

Therapies for the Treatment of Immuno-inflammatory Conditions

Health Tech & Life Sciences
Acquired (Inactive) by Menlo Therapeutics on Nov 2019 - ceased to operate
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Company Overview

Snapshot

Founded in January 2003 by Meir Eini, VYNE Therapeutics operates with 51–200 employees. The company has raised $180M across four funding rounds from two investors. In November 2022, VYNE Therapeutics announced the first subjects dosed in a Phase 1a/b clinical trial evaluating its Pan-BET Inhibitor, VYN201, for the treatment of Vitiligo.

Business overview

VYNE Therapeutics is a biopharmaceutical company focused on developing proprietary and differentiated therapies for immuno-inflammatory conditions. The company leverages its Molecule Stabilizing Technology to develop and commercialize solutions, including FDA-approved AMZEEQ (minocycline) topical foam, 4%, for topical minocycline, and ZILXI (minocycline) topical foam, 1.5%, for rosacea treatment. VYNE Therapeutics serves the dermatology and broader pharmaceutical markets, operating within the Health Tech & Life Sciences sector.

Strategic signal

In January 2023, VYNE Therapeutics announced that the first vitiligo patient was dosed in the Phase 1a/b clinical trial for its novel BET Inhibitor VYN201. This advancement signals the company's continued commitment to developing innovative treatments for immuno-inflammatory conditions and expands its pipeline beyond its existing FDA-approved topical foam products, indicating potential for future growth in new therapeutic areas.

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Company Intelligence Q&A

What was a significant recent clinical development for VYNE Therapeutics?
In January 2023, VYNE Therapeutics announced the first vitiligo patient was dosed in the Phase 1a/b clinical trial for its novel BET Inhibitor VYN201.
When did VYNE Therapeutics announce the availability of ZILXI in pharmacies?
In October 2020, VYNE Therapeutics announced that ZILXI (minocycline) topical foam, 1.5% became available in pharmacies nationwide.
What was a key corporate change for the company in 2020?
In September 2020, Menlo Therapeutics completed its corporate name change to VYNE Therapeutics, following its merger with Foamix Pharmaceuticals.
Which investors participated in the July 2019 funding round?
In July 2019, the company raised funding from investors including Perceptive Advisors and OrbiMed.
What was a notable regulatory milestone for Foamix Pharmaceuticals before the merger?
In March 2019, Foamix announced FDA acceptance of its New Drug Application for FMX101 Minocycline Foam for the treatment of moderate to severe acne.
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